piperacilline/tazobactam

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01C - Beta-Lactam Antibacterials, Penicillins -> J01CR - Combinations Of Penicillins, Incl. Beta-Lactamase Inhibitors -> J01CR05 - Piperacillin And Enzyme Inhibitor
Administration category: Free Medicine group: antibacterial File parts: piperacilline tazobactam Brand name: Tazocin

Safety margins

≥ 18 years
WeightROADosage
ROA:
iv
Dosage:
min. 4000/500mg 3 dd to max. 4000/500mg 4 dd
ROA:
iv
Dosage:
to max. 18000/2250mg/24h in 4 doses

Kidney function

≥ 18 years
ROAGFRDosageIntervalComments
ROA: iv
GFR:
30 - 50
Dosage:
4000/500
Interval:
8 Hours
GFR:
10 - 30
Dosage:
4000/500
Interval:
12 Hours
Renal elimination: piperacilline ? %, tazobactam 80%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: iv 4000/500 mg pip-tazo elke 12 uur

Hemo dialysis: iv 4000/500 mg pip-tazo elke 12 uur, na elke dialyseperiode een extra dosis van 2000/250 mg pip-tazo

CAV / VVHD: aanpassing van de dosering is niet noodzakelijk

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1696.4
Updated: 06/16/2019 - 20:05
Status: Published

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