endocarditis

Advices

≥ 18 years
Priority Medication Remarks
Medication:

amoxicilline iv 2g 6dd

+

ceftriaxon iv 2g 2dd

Remarks:

Natieve klep; subacuut begin; empirische therapie 

Medication:

flucloxacilline iv 2g 6dd

or

flucloxacilline iv 12g continuous per 24 hours

Remarks:

Natieve klep; acuut begin; empirische therapie

Medication:

flucloxacilline iv 2g 6dd

+

vancomycine iv 1000mg min 2dd max 3dd

Remarks:

Kunstklep; empirische therapie

≥ 18 years

Indications: Bij allergie voor penicilline

Priority Medication Remarks
Medication:

ceftriaxon iv 2g 1dd

+

vancomycine iv 1000mg min 2dd max 3dd

Remarks:

Natieve klep; subacuut begin; empirische therapie 

Medication:

cefazoline iv 1g 6dd

or

cefazoline iv 6g continuous per 24 hours

Remarks:

Natieve klep; acuut begin; empirische therapie 

Medication:

cefazoline iv 1g 6dd

+

vancomycine iv 1000mg min 2dd max 3dd

Remarks:

kunstklep; empirische therapie

≥ 18 years

Indications: Ernstige allergie voor betalactams

Priority Medication Remarks
Medication:

vancomycine iv 1000mg min 2dd max 3dd

Remarks:

Natieve klep; acuut begin; empirische therapie

Comments

- Vancomycine 2000-3000mg/dag in 2-3 doses (dalspiegels 15-20 mg/l). Alternatief is continu infuus (streefspiegel 20-25 mg/l).

 

- Empirische therapie aanpassen op geleide kweek. zie SWAB richtlijn

 

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-8500.2
Updated: 11/01/2019 - 08:56
Status: Published